Just got word from Haddad that they have posted a new tweak guide for Command & Conquer: Renegade. Here's a quote from their guide:

Command & Conquer: Renegade represents Westwood's first foray into setting a FPS game in the C&C universe on the PC & has been met with a mixed enough response. 3D Spotlight's new tweak guide will take you through setting up the game, along with other informational tips regarding graphics, audio and controls.

Command & Conquer: Renegade tweak guide